Göttingen is located directly off the 'Autobahn' A7 between Hannover and Kassel.
A7 is the longest German Autobahn and the longest national motorway in Europe, from the Danish border in the north to the Austrian border in the south.
There are two Göttingen exits. Please consult a map for the most convenient exit.

Most IC (Intercity) and ICE (Intercity Express) trains on the North/South, East/West routes stop in Göttingen. There is a direct train from Frankfurt Airport. From Göttingen station you can either take a taxi to wherever your accommodation is, or take a bus from the central bus station, which is located next to the train station. However, your hotel most probably is reachable by foot!

The nearest airport is Hannover, but you will often find cheaper tickets to fly to Frankfurt International Airport. Hannover Airport has regular train connections to Göttingen (with transfer at Hannover central train station). Frankfurt Airport has its own train station with direct train connections to Göttingen (however some train connections require a transfer at Frankfurt central train station).